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Meanwhile, clinical studies in healthy volunteers who were given alcohol and bupropion failed to show any significant drug interaction between these compounds.

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glaxo then developed a sustained-release sr version which releases bupropion hydrochloride at a slower rate.

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healthy elderly patients do not appear to be more sensitive to side effects of bupropion than younger adults and do not require reduced doses.

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clinicians should be aware that digoxin levels may rise on discontinuation of bupropion and the patient should be monitored for possible digoxin toxicity.

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